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16-bit I2C General Purpose IO Expander with Interrupt & Reset

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The PI4IOE5V6416A is a 16-bit general-purpose I/O expander that provides remote I/O expansion for most microcontroller families via the I2C-bus interface.

It provides a simple solution when additional I/Os are needed while keeping interconnections to a minimum, for example, in battery0powered mobile applications for interfacing to sensors, push buttons, keypad, etc.

It can operate from 1.65V to 5.5V on the GPIO-port side and 1.65V to 5.5V on the SDA/SCL side. This allows the PI4IOE5V6416A to interface with next generation microprocessors and microcontrollers on the SDA/SCL side, where supply levels are dropping down to conserve power.

The bidirectional voltage-level translation in the PI4IOE5V6416A is provided through VDD(I2C_bus. VDD(I2C_bus) should be connected to the V­DD of the external SCL/SDA lines. The voltage level on the GPIO-port of the PI4IOE5V6416A is determined by VDD(P).

At power on, the I/Os are configured as inputs; however, the system master can enable the I/Os as either inputs or outputs by writing to the I/O direction bits. The data for each input or output is kept in the corresponding Input or Output register. All registers can be read by the system master.

PI4IOE5V6416A has open-drain interrupt (INT) output pin that goes LOW when in the input state of a GPIO-port changes from the input-state default register value. The device also has an interrupt masking feature by which the user can mask the interrupt from an individual GPIO-port.


  • Operation power supply voltage from 1.65V to 5.5V
  • Allows bidirectional voltage-level translation and GPIO expansion between
    • 1.65V to 5.5V SCL/SDA and 1.65V to 5.5V Port
  • Low standby current consumption
    • 1.5µA typical at 5V VDD
    • 1µA typical at 3.3V VDD 
  •  400kHz I2C-bus interface
  • Compliant with the I2C-bus Fast and Standard modes
  • Programmable Push-pull/Open-drain output stages
  • Programmable output drive strength and pull-up/down resistor
  • Power-on reset
  • Active LOW open-drain interrupt output
  • Active LOW reset input
  • Latch-up tested (exceeds 100mA)
  • Totally Lead-Free & Fully RoHS Compliant (Notes 1 & 2)
  • Halogen and Antimony Free. "Green" Device (Note 3)
  • For automotive applications requiring specific change control (i.e. AEC-Q100/101/104/200, PPAP capable, and manufactured in IATF 16949 certified facilities), please contact us or our local Diodes representative. https://www.diodes.com/quality/product-definitions/ 
  • Packaging (Pb-free & Green):
    • 24-pin, TQFN (ZD)
    • 24-Pin, TSSOP (L)

Product Specifications

Product Parameters

Compliance (Only Automotive supports PPAP) Standard
Analog or Digital? Digital
Voltage 1.65V  to  5.5V
Single Ended Channels 16
Signal Type Single Ended
Configuration 16 bits
Ambient or Junction Temperature (°C) -40 to 85

Technical Documents

Recommended Soldering Techniques


Additional Technical Documents are available upon request:
Application information, Evaluation board, and Other technical documents

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